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Dokumentation 35
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Effectiveness of selected materials against Enterococcus
faecalis: part 3. The antibacterial effect of calcium hydroxide and
chlorhexidine on Enterococcus faecalis.
Lin YH, Mickel AK, Chogle S.
Department of Endodontics, Case Western Reserve University, School of
Dentistry, Cleveland, OH 44106-4905, USA.
It has been found that Enterococcus faecalis is most commonly isolated in
failed endodontic treatment. Irrigation with chlorhexidine gluconate has
been suggested based on its antimicrobial effect and substantivity. Calcium
hydroxide also is an effective antimicrobial agent because of its high
alkalinity. The purpose of this study was to test the individual and
combined effect of calcium hydroxide and chlorhexidine against E. faecalis.
The agar-diffusion test was performed on Mueller-Hinton plates. Paper disks
were impregnated with: (a) CaOH powder with sterile water; (b) Pulpdent; (c)
0.12% Peridex; (d) CaOH powder with Peridex; and (e) Pulpdent with Peridex.
Ampicillin served as a control. The plates were incubated at 37 degrees C
for 72 h. Peridex showed significantly larger zones of inhibition compared
with CaOH. No statistically significant difference was found between Peridex
and the combination of CaOH and Peridex.
- Die Autoren untersuchen die Wirksamkeit von Chlorhexidin und verschiedenen
Zubereitungen von Ca(OH)2 auf E. Faecalis mit Hilfe eines
agar-Diffusisontestes, wobei Chlorhexidine eine deutlich größere
Inhibitionszone zeigte als Ca(OH)2, welches in welcher Galenik auch
immer eine ausgesprochen geringe Wirkung hatte (nahezu unwirksam). Die
Kombination von CHX und Ca(OH)2 hatte keine größere Wirkung als CHX
alleine.
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